2011
  • Rachel Grange, Thomas Lanvin, Chia-Lung Hsieh, Ye Pu, and Demetri Psaltis, Biomedical Optics Express 2(9), 2532–2539 (2011) Website
    Imaging with second-harmonic radiation probes in living tissue.
We demonstrate that second-harmonic radiation imaging probes are efficient biomarkers for imaging in living tissue. We show that 100 nm and 300 nm BaTiO(3) nanoparticles used as contrast markers could be detected through 50 $μ$m and 120 $μ$m of mouse tail tissue in vitro or in vivo. Experimental results and Monte-Carlo simulations are in good agreement.