Dr. Chia-Lung Hsieh (謝佳龍) is a principal investigator of the Institute of Atomic and Molecular Science (IAMS) at Academia Sinica in Taiwan. His research focuses on the development of optical microscope techniques for studying biological systems. His current investigations rest on the use of ultrahigh-speed interferometric laser microscopy to resolve dynamics in biological cells. Dr. Hsieh also exploits image processing and data analysis for quantitative reconstruction of cellular activities with molecular details. The impact of his research covers the field of optical microscopy, membrane biophysics, single-molecule techniques, and nanoparticle technology.
Dr. Hsieh’s lab has three main research emphases: (1) Developing new optical microscope techniques for label-free bioimaging and sensing. (2) Employing ultrahigh-speed interferometric laser microscopy to resolve single-molecule dynamics and organization of cell membranes at the nanometer length scale and microsecond time scale. (3) Investigating virus-receptor interaction in the early-stage viral infection.
Due to his significant academic achievements and research potential, Dr. Hsieh was awarded the Young Scholars' Creativity Award from Foundation for the Advancement of Outstanding Scholarship (2020), and the Junior Research Investigator Award (2019) and the Career Development Award (2017) of Academia Sinica. His research work on "monovalent nanoparticle labeling to single membrane molecules" and "ultrahigh-speed single-virus imaging by coherent brightfiled microscopy" were recognized as the Significant Research Achievements of Academia Sinica in 2019 and 2017, respectively. He also received the Taiwan Merit Scholarship, the Dr. Bor-Uei Chen Memorial Scholarship Award, and the Acer Long Term Distinguished Paper Award.
Dr. Hsieh received his PhD degree from Caltech in 2011 under the supervision of Prof. Demetri Psaltis. During his PhD studies, he investigated nonlinear optics in nano-sized particles and their applications to bioimaging. Much of his PhD research was accomplished in the Optics Laboratory at EPFL in Switzerland when he was an exchanged PhD student from 2007 to 2011. After graduation, he moved to Max Planck Institute for the Science of Light in Erlangen, Germany for his postdoctoral studies, and worked on interferometric scattering (iSCAT) microscopy and single-particle tracking with Prof. Vahid Sandoghdar. In December of 2012, he joined IAMS as a PI and founded Bio-Nano-Photonics Lab.
Address: No. 1, Roosevelt Rd. Sec. 4, IAMS, Academia Sinica, Taipei 10617, Taiwan