Nano-Bio-Photonics Lab is a multidisciplinary research team located at the Institute of Atomic and Molecular Sciences (IAMS), Academia Sinica, Taiwan. We develop new optical microscope techniques and novel data analytical methods, aiming to elucidate fundamental physics and chemistry events in living systems at the nanoscale. By combining molecular biological approaches and advanced optical technology, we experimentally measure the dynamics of individual biological nano-objects, from single viruses to single molecules, at high spatiotemporal resolution. These small objects move rapidly in biological cells due to the thermal fluctuation, constantly interacting with the surrounding environments. Our goal is to understand how life is constructed based on these stochastic events. We believe that these studies will shed new light on the origin of diseases, including viral infection and neuronal signaling.

In order to perform the research above, we develop new techniques for optical observation, microscopic manipulation, nanoparticle labeling, and data analysis....