ABOUT
Nano-Bio-Photonics Lab is a multidisciplinary research team located at the Institute of Atomic and Molecular Sciences (IAMS), Academia Sinica, Taiwan. We develop new optical microscope techniques and novel data analytical methods, aiming to elucidate fundamental physics and chemistry events in living systems at the nanoscale. By combining molecular biological approaches and advanced optical technology, we experimentally measure the dynamics of individual biological nano-objects, from single viruses to single molecules, at high spatiotemporal resolution. These small objects move rapidly in biological cells due to the thermal fluctuation, constantly interacting with the surrounding environments. Our goal is to understand how life is constructed based on these stochastic events. We believe that these studies will shed new light on the origin of diseases, including viral infection and neuronal signaling.
In order to perform the research above, we develop new techniques for optical observation, microscopic manipulation, nanoparticle labeling, and data analysis....
In order to perform the research above, we develop new techniques for optical observation, microscopic manipulation, nanoparticle labeling, and data analysis....
RESEARCH
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Label-Free ImagingUsing advanced scattering-based interference microscopy and novel image data analysis, we ...
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Advanced MicroscopyWe develop advanced optical techniques that detect linear scattered light from small parti...
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Single MoleculesWe use novel optical microscope techniques combined with sophisticated data analysis to re...
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Virus and MembraneUnexpected disease outbreaks caused by rare infectious agents from different continents ha...
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AlgorithmsWe develop advanced image processing algorithm to enhance signal-to-noise ratio for high-p...